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Effect of pre-treatment processes and stability testing of lemongrass (Cymbopogon citratus) extract on ?-glucosidase inhibitor (AGI) and ?-amylase inhibitor (AAI) activities |
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| รหัสดีโอไอ | |
| Title | Effect of pre-treatment processes and stability testing of lemongrass (Cymbopogon citratus) extract on ?-glucosidase inhibitor (AGI) and ?-amylase inhibitor (AAI) activities |
| Creator | Diah Widiputri Nadya Mariana Blandina Josopandojo, Maria Gunawan-Puteri Irvan Kartawiria 1 |
| Contributor | Department of Chemical Engineering Faculty of Life Sciences and Technology Swiss German University Tangerang Indonesia |
| Publisher | Mahasarakham University |
| Publication Year | 2560 |
| Keyword | lemongrass AGI AAI diabetes |
| Abstract | Lemongrass was proved in the previous studies to be one of Indonesian local plants with relatively high activity in inhibiting ?-glucosidase and ?-amylase enzymes and thus it can be useful to lower blood glucose level in diabetic patients. This health benefit of lemongrass has unfortunately not been widely explored in the herbal industries. Even though lemongrass has become one of the main raw materials in such industries, the use of lemongrass has been purposed mostly to obtain its aroma and taste. Commercialization of lemongrass as herbal medicine or functional food ingredients with ?-glucosidase Iinhibitor (AGI) and ?-amylase inhibitor (AAI) activities requires a closer study on how these activities can be affected by different pre-treatment processes of fresh lemongrass. In this work, the effect of different washing and drying scenarios during the pre-treatment process of lemongrass extraction on both AGI and AAI activities was studied. The result showed that a combination between 2 times washing and oven drying at 40ฐC offered the optimum AGI activity. The AAI level was found to be significantly decreased as lemongrass had gone through drying process. However, when compared among different drying methods and different sequences of washing process, the AAI level was found to be relatively unaffected. Stability testing of powdered lemongrass extract was additionally conducted in real time and accelerated conditions to make an estimation of the shelf-life. The shelf-life of powdered lemongrass extract was found to be ฑ12 months (at 25ฐC) and ฑ 6 months (at 30ฐC). |
