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Bioactive compounds from sponge-derived fungus strain CRI 247-01 and soft coral-derived fungus strain CRIF1 |
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| รหัสดีโอไอ | |
| Title | Bioactive compounds from sponge-derived fungus strain CRI 247-01 and soft coral-derived fungus strain CRIF1 |
| Creator | Chairut Kasettrathat |
| Contributor | Nattaya Ngamrojanavanich, Khanitha Pudhom |
| Publisher | Chulalongkorn University |
| Publication Year | 2550 |
| Keyword | Bioactive compounds, Fungi, Sponges, Corals, สารออกฤทธิ์ทางชีวภาพ, เชื้อรา, ฟองน้ำ, ปะการัง |
| Abstract | Chemical constituents of two marine-derived fungi, strains CRI 247-01 and CRIF1, were investigated. The sponge-derived fungus strain CRI 247-01 gave a new compound 2, along with two known compounds, 6-methoxymellein (compound 1) and vermillhotin (compound 3). While, a new compound 4 was isolated from the strain CRIF1 which was isolated from a soft coral. Moreover, derivatives of compound 4, methylester (compound 5), benzylester (compound 6), and hydrogenated product (compound 7) were prepared. Chemical structures of these compounds were elucidated on the basis of their spectroscopic data. In this study, compounds 3, 5, and 6 exhibited potent cytotoxic activity against cancer cell lines. Moreover, compound 6 also inhibited antioxidant activity (HL-60 Antioxidation) |
| URL Website | cuir.car.chula.ac.th |
