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Extraction of Centella asiatica leaves using a mixture ofsubcritical dimethyl ether and ethanol: Optimization of conditionsby response surface methodology |
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| รหัสดีโอไอ | |
| Creator | 1. Chitaporn Pingyod 2. Neti Waranuch 3. Watoo Phrompittayarat 4. Panatpong Boonnoun 5. Kornkanok Ingkaninan |
| Title | Extraction of Centella asiatica leaves using a mixture ofsubcritical dimethyl ether and ethanol: Optimization of conditionsby response surface methodology |
| Publisher | Research and Development Office,Prince of Songkla University |
| Publication Year | 2021 |
| Journal Title | Songklanakarin Journal of Science and Technology (SJST) |
| Journal Vol. | 43 |
| Journal No. | 3 |
| Page no. | 711-718 |
| Keyword | Centella asiatica, response surface optimization, triterpenoid saponins, dimethyl ether, extraction |
| URL Website | https://rdo.psu.ac.th/sjstweb/ |
| ISSN | 0125-3395 |
| Abstract | This study aimed to develop an effective extraction method to recover triterpenoid saponins from Centella asiatica (L.)Urban leaves using a mixture of subcritical dimethyl ether (DME) and ethanol (EtOH) as extractant. The optimal extractionconditions, as suggested by response surface methodology, were a mixture of 2.9 ml EtOH and 5.3 g subcritical DME per g ofsample at 48.7ยบC. It can provide 18.8% of total triterpenoid saponins (weight/ dry weight of C. asiatica) which is 2- to 4-fold thatobtained from the extractions with only EtOH (9.3%) or only subcritical DME (4.8%) under the same conditions. |
