The Anti-Diabetic Effect of Nano-Encapsulated Propolis from Apis melliferaon Type 2 Diabetes
รหัสดีโอไอ
Creator Sarah S. Hegazy
Title The Anti-Diabetic Effect of Nano-Encapsulated Propolis from Apis melliferaon Type 2 Diabetes
Contributor Hanan Helmy, Mohamad S. Salama, Nadia M. Lotfy and Dalia M. Mahmoud
Publisher King Mongkut's Institute of Technology Ladkrabang
Publication Year 2564
Journal Title Current Applied Science and Technology
Journal Vol. 21
Journal No. 1
Page no. 88-103
Keyword diabetes mellitus, chitosan, polyacrylic acid, propolis, body weight
URL Website https://www.tci-thaijo.org/index.php/cast
Website title https://www.tci-thaijo.org/index.php
ISSN 2586-9396
Abstract Diabetes mellitus is viewed as a major disease and isamong the most prevalent health problems globally. The goal of the present research was to evaluate the therapeutic efficiency of an ethanolic extract of Egyptian propolis (EEP) conjugated with chitosanpolyacrylic(CS-PAA) nanoparticlesagainst type 2 diabetes mellitus. Thirty Wistar rats were randomly categorized into 6 groups (5 animals/group). Group I consisted of normal rats as a normalcontrol. The remaining five groups were injected with streptozotocin (STZ), a diabetogenic agent, in order to induce diabetes. The experimental groups were treated for 4 consecutive weeks as follows: Group II included untreated diabetic rats, serving as a negativecontrol. Group III consisted of diabetic rats treated with EEP. Group VI consisted of diabetic rats treated with Metformin. The findings of this work illustrated that no significant differences were noticed concerning the body weight of the treated groups compared to that of the normal control group. Blood glucose levels were significantly decreased in the diabetic rats treated with EEP and EEP encapsulated CS-PAA nanoparticles compared to the untreated diabetic rats. The results indicated that EEP encapsulated CS-PAA nanoparticles displayed a potential therapeutic effect against type 2 diabetes mellitus.
สถาบันเทคโนโลยีพระจอมเกล้าเจ้าคุณทหารลาดกระบัง

บรรณานุกรม

EndNote

APA

Chicago

MLA

ดิจิตอลไฟล์

Digital File
DOI Smart-Search
สวัสดีค่ะ ยินดีให้บริการสอบถาม และสืบค้นข้อมูลตัวระบุวัตถุดิจิทัล (ดีโอไอ) สำนักการวิจัยแห่งชาติ (วช.) ค่ะ