Acute Cholestatic Hepatitis Induced by Epstein-Barr virus (EBV) Infection in a Child: A Case Report
รหัสดีโอไอ
Creator Chanakan Tanjararak
Title Acute Cholestatic Hepatitis Induced by Epstein-Barr virus (EBV) Infection in a Child: A Case Report
Publisher Text and Journal Publication
Publication Year 2564
Journal Title Vajira Medical Journal
Journal Vol. 65
Journal No. 5
Page no. 425-432
Keyword hepatitis, cholestasis, Epstein-Barr virus
URL Website https://tci-thaijo.org/index.php/VMED
Website title Vajira Medical Journal (วชิรเวชสาร)
ISSN 0125-1252
Abstract Primary Epstein-Barr virus (EBV) infection occurs frequently in children and causes various clinical manifestations. The patients may be asymptomatic and spontaneously recover from infection or has severe symptoms with fatal complication. The frequent manifestations include fever, exudative pharyngotonsillitis, and lymphadenopathy. EBV infection leads to mild and selflimited increase in liver enzymes. However, clinical manifestations of hepatitis including jaundice are very rare in children, with only several cases previously reported in the medical literature. We report a case of an 11 years 8 months old girl who was hospitalized because of cholestatic hepatitis induced by EBV infection. EBV infection should be considered in the differential diagnosis of cholestatic hepatitis in children, in order to avoid unnecessary investigations.
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