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Exercise and Cognitive Functions in People with Mild to Moderate Alzheimer's Disease: A Systematic Review |
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| รหัสดีโอไอ | |
| Creator | Thanyaporn Wongwatcharanon |
| Title | Exercise and Cognitive Functions in People with Mild to Moderate Alzheimer's Disease: A Systematic Review |
| Publisher | Text and Journal Publication |
| Publication Year | 2561 |
| Journal Title | Vajira Medical Journal |
| Journal Vol. | 62 |
| Journal No. | 2 |
| Keyword | Alzheimer, exercise, combined exercise, cognitive function, systematic review |
| URL Website | https://tci-thaijo.org/index.php/VMED |
| Website title | Vajira Medical Journal (วชิรเวชสาร) |
| ISSN | 0125-1252 |
| Abstract | Background: Alzheimer's disease is a neurodegenerative disease, a progressive brain disorder that slowly declines cognitive functions. Furthermore, a higher incidence rate and prevalence have been reported in older adults. Several studies have been reported that exercise might be an intervention to delay cognitive decline in older people. Objective: To determine a type of exercise that appropriate on cognition in people with mild to moderate severity of Alzheimer's disease Methods: The literature searches focused on PubMed, Cochrane Library, PEDro, and ScienceDirect from 1978 to December 2017. The inclusion criteria were randomized control trials studies, non-randomized control trials studies that examined the effect of exercise on cognitive function in people with mild to moderate severity of Alzheimer's disease (AD), and all journal articles were published in English languages. In addition, the reviewers independently screened the trials for eligibility criteria. Data extraction from each of the studies was completed in detail by one reviewer and accuracy was checked by another reviewer. Results: Of the 6344 studies, only six studies were included in the review. The level of quality was poor to good level with an average PEDro scale was 5.4. It has been found that different types of exercise such as balance exercise, endurance or aerobic exercise, resistance or strengthening exercise, affected on cognition in people with AD. However, a number of clinical studies reported that combined exercise had high effectiveness in delaying cognitive impairment in people with AD. However, two studies reported that there was no significant difference between groups and between before and after training whereas four studies showed significant difference in cognition between before and after training. Conclusions: Combined exercise may be appropriate to delay the cognitive function in people with Alzheimer's disease. |
