Bedtime Dosing of Antihypertensive Drugs in Chronic Kidney Disease Patients with Hypertension
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Creator Wannakon Chuemongkon, Nalinee Kruetiwa
Title Bedtime Dosing of Antihypertensive Drugs in Chronic Kidney Disease Patients with Hypertension
Publisher Text and Journal Publication
Publication Year 2558
Journal Title Vajira Medical Journal
Journal Vol. 59
Journal No. 2
Page no. 75-84
Keyword Chronic kidney disease, hypertension, bedtime dosing of antihypertensive drugs, non-dipper
ISSN 0125-1252
Abstract Chronic kidney disease patients with hypertension whose blood pressure remained above goal resulted in subsequent deterioration in renal function and was at high risk of cardiovascular diseases. These remarkably impacted on patients with non-dipping blood pressure pattern. Accordingly, many studies revealed that nocturnal ambulatory blood pressure, the prevalence of non-dipper pattern, decline in estimated glomerular filtration rate and risk of cardiovascular events were reduced by taking at least one antihypertensive drug at bedtime rather than in the morning in chronic kidney disease patients with hypertension, especially with the non-dipping blood pressure pattern.
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