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Practice of Antibiotic Prophylaxis in Abdominal Hysterectomy at King Chulalongkorn Memorial Hospital |
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| รหัสดีโอไอ | |
| Creator | Gunta Prawai |
| Title | Practice of Antibiotic Prophylaxis in Abdominal Hysterectomy at King Chulalongkorn Memorial Hospital |
| Contributor | Surasith Chaithongwongwatthana |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2566 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 31 |
| Journal No. | 3 |
| Page no. | 208-214 |
| Keyword | antibiotic prophylaxis, hysterectomy, practice |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To evaluate the rate of adherence to the guidelines for antibiotic prophylaxis using in elective abdominal hysterectomy. Materials and Methods: Retrospective descriptive study was conducted by reviewing medical records of women underwent elective abdominal hysterectomy at King Chulalongkorn Memorial Hospital (KCMH) from January to December 2019. Cases who having bacterial infection, surgical procedures on gastrointestinal or urinary tract, operative time longer than 3 hours, blood loss more than 1,500 milliliters, immunosuppression, or receiving immunosuppressive agents were excluded. Logistic regression analysis was used to determine factors associated with appropriate use of antibiotics prophylaxis.Results: A total of 588 women underwent elective abdominal hysterectomy in the study period. Among 391 eligible patients with a mean age of 48.7 years, 326 cases (83.4%) had benign diseases on final diagnosis. Most of the operations used transverse skin incision and a median operative time and blood loss were 90 minutes and 200 milliliters, respectively. Use of antibiotics prophylaxis that adherent to the guidelines was demonstrated in 63 cases (16.1% of all cases, 19.3% of cases without staging procedures). Among cases without staging procedures, operation by residents was the only factor that significantly increased appropriate use of antibiotics prophylaxis with adjusted odds ratio of 6.84 (95% confidence interval 3.40-13.74).Conclusion: Uses of antibiotic prophylaxis for abdominal hysterectomy at KCMH were mostly not adherent to the guidelines. An antibiotic stewardship program needs to be implemented to improve the practice. |
