Lidocaine Infiltration in Mesosalpinx for Reducing Operative Time in Postpartum Tubal Sterilization: A randomized, controlled trial
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Creator Vichunee Nithiwatthanasak
Title Lidocaine Infiltration in Mesosalpinx for Reducing Operative Time in Postpartum Tubal Sterilization: A randomized, controlled trial
Contributor Jesada Wutitammasuk
Publisher PIMDEE Co., Ltd.
Publication Year 2565
Journal Title Thai Journal of Obstetrics and Gynaecology
Journal Vol. 30
Journal No. 1
Page no. 33-40
Keyword lidocaine, mesosalpinx, postpartum, tubal sterilization, operative time, pain score
URL Website https://tci-thaijo.org/index.php/tjog/index
Website title www.tci-thaijo.org
ISSN 2673-0871
Abstract Objectives: To evaluate the efficacy and dosage of lidocaine infiltration in mesosalpinx for reducingoperative time in postpartum tubal sterilization.Materials and Methods: A randomized, double-blinded, placebo-controlled trial was conducted in105 women at Khon Kaen Hospital between April and July 2020. The participants were randomlyassigned into three groups 4 ml of 2% lidocaine, 1% lidocaine, and normal saline solution (NSS)infiltrated in the mesosalpinx. Systemic sedative drugs were administered before the procedurein all groups. Operative time from skin incision to closure was recorded. Intra-operative,immediately and 1 hour post-operative pain score were evaluated.Results: Age and body mass index were not statistically different between 2% lidocaine, 1% lidocaine,NSS groups (29.00 ? 4.54, 30.37 ? 5.92, 31.03 ? 5.08 yrs. and 25.08 ? 3.14, 25.88 ? 2.82, 26.08? 2.60 kg/m2, respectively). Other baseline characteristics including postpartum duration beforesterilization, parity, gestational age, and level of surgeon experience were similar across groups.Mean operative time for 2% lidocaine, 1% lidocaine, and NSS group was 17.9 ? 6.19, 21.6 ?9.72, and 23.1 ? 12.04 min. The operative time of 2% lidocaine was significantly shorter thanNSS (p = 0.027), and pain scores in 2% lidocaine were significantly lower than for NSS for allperiods. The operative time of 1% lidocaine was not significantly different compared to NSSwhereas 1% lidocaine had a significantly lower pain score only immediately and 1 hour postoperation. There were no serious adverse events found.Conclusion: Two percent lidocaine infiltration in the mesosalpinx significantly shortened operativetime and could reduce pain throughout postpartum tubal sterilization.
Thai Journal of Obstetrics and Gynaecology

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