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Medical Abortion at Gestational Age ? 24 weeks at Songklanagarind Hospital |
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| รหัสดีโอไอ | |
| Creator | Wannaporn Sudsai |
| Title | Medical Abortion at Gestational Age ? 24 weeks at Songklanagarind Hospital |
| Contributor | Chitkasaem Suwanrath, Thanapan Choobun |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2565 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 30 |
| Journal No. | 3 |
| Page no. | 198-206 |
| Keyword | medical abortion, mifepristone, misoprostol, complicationtranslabial ultrasound |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To determine the success and complication rates of medical abortion at gestational age ? 24 weeks, and to identify their associated factors.Materials and Methods: A retrospective study was conducted from January 2006 to December 2017. Medical records of pregnant women at gestational age ? 24 weeks, who were admitted for medical abortion, were reviewed. Spontaneous abortion was excluded. Multivariate logistic regression analysis was used to identify factors associated with success and complications. A p value of < 0.05 was considered statistically significant.Results: A total of 717 cases were reviewed. Two medical regimens were used, including misoprostol alone (84.7%) and mifepristone-misoprostol (MM) (15.3%). The overall success rates in the first and second trimester were 65.8% and 79.3%. The highest success rate was observed in women at gestational age of ? 9 weeks, with the MM regimen (92.0%). The overall complication rate was 5.3%, including hemorrhage requiring blood transfusion (4.7%) and infection (0.6%). The complication rates in the first and second trimester were 2.5% and 5.6%, respectively. One factor associated with success in the first trimester was the drug regimen (MM); while that in the second trimester was maternal age. Multivariate analysis showed that factors associated with complications in the second trimester were multigravida and having an underlying disease.Conclusion: Medical abortion at gestational age ? 24 weeks had low complications. Multigravida and having an underlying disease were factors associated with complications in the second trimester. |
