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Lidocaine Prilocaine Cream in Conjunction with Paracervical Block versus Placebo with Paracervical Block for Pain Relief during Fractional Curettage |
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| รหัสดีโอไอ | |
| Creator | Bordin Duangrudeesawat |
| Title | Lidocaine Prilocaine Cream in Conjunction with Paracervical Block versus Placebo with Paracervical Block for Pain Relief during Fractional Curettage |
| Contributor | Sukanya Srinil |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2565 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 30 |
| Journal No. | 2 |
| Page no. | 120-127 |
| Keyword | fractional curettage, lidocaine prilocaine cream, paracervical block, visual analog scale |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To study the efficacy of lidocaine prilocaine cream apply at cervix in conjunction withparacervical block versus placebo with paracervical block for pain reduction during fractionalcurettage.Materials and Methods: One hundred and six women who underwent fractional curettage at KhonKaen Hospital were enrolled in a randomized, double-blinded, placebo-controlled trial. Theparticipants were randomly allocated into two groups, received lidocaine prilocaine cream plusparacervical block applied onto cervix (n = 53) versus placebo cream plus paracervical block(n = 53) before performing fractional curettage. Pain score was measured at tenaculumplacement, during procedure, immediately after and 30 minutes after the procedure, using a 10centimeters visual analog scale (VAS). The adverse events and additional analgesia were alsorecorded.Results: Baseline characteristics were similar between groups. Mean pain score during fractionalcurettage in lidocaine prilocaine cream plus paracervical block was significantly lower thanplacebo cream plus paracervical block (2.80 ? 0.29, 95% confidence interval (CI) 2.21-3.38 vs.5.34 ? 0.39, 95%CI 4.55-6.13, p < 0.001). Adverse events such as lightheadedness, palpitationand tinnitus were found without statistically significant difference between groups. None of theparticipants requested an additional analgesia.Conclusion: Lidocaine prilocaine cream in conjunction with paracervical block had better pain reliefduring fractional curettage than in control group without serious adverse events. |
