Treatment of Anogenital Warts: Siriraj Hospital Experience
รหัสดีโอไอ
Creator Manopchai Thamkhantho
Title Treatment of Anogenital Warts: Siriraj Hospital Experience
Contributor Chenchit Chayachinda
Publisher PIMDEE Co., Ltd.
Publication Year 2563
Journal Title Thai Journal of Obstetrics and Gynaecology
Journal Vol. 28
Journal No. 2
Page no. 120-127
Keyword anogenital warts, treatment
URL Website https://tci-thaijo.org/index.php/tjog/index
Website title www.tci-thaijo.org
ISSN 2673-0871
Abstract Objectives: To demonstrate the characteristics, treatment modalities and outcomes in the women presenting with Anogenital Warts (AGW) at Female STI Clinic, Siriraj Hospital.Materials and Methods: The outcomes of treatment in the patients presenting with AGW who had complete follow-up at Siriraj Female STI clinic in 2016 were reviewed. The patients with immunocompromised conditions such as systemic lupus erythematosus and human immunodeficiency virus infection were excluded from this study. Results: Two hundred and four of 217 women with AGW were eligible for this study. The mean age was 24.6 ? 5.2 years. Most of them were married and had sexual monogamy. Education levels were similar. Most of the AGWs were located outside the vagina and with ? 5 lesions (range 1-20). The diameter of warts was between 1 and 5 cm. The treatment modalities were 85% trichloroacetic acid (TCA) 131 (64.3%), 5% imiquimod 57 (27.9%), cryotherapy 8 (3.9%) and surgery 8 (3.9%). The median periods of treatment were 4, 8, 5 and 1 weeks for 85% TCA, 5% Imiquimod, Cryotherapy and Surgery, respectively. Treatment modalities were changed in the groups of 85% TCA and 5% Imiquimod, for 16.0% and 1.8%, respectively. Recurrence at 3 months after being cured was highest in the groups of 85% TCA (13.0%).Conclusion: Our results showed that 85% TCA, which is widely available, need four applications with 13% recurrence rate. Imiquimod took longer time for treatment but was associated with less recurrent. Cryotherapy and Surgery showed promising results but the data were limit.
Thai Journal of Obstetrics and Gynaecology

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