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Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial |
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| รหัสดีโอไอ | |
| Creator | Sasitorn Wongart |
| Title | Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial |
| Contributor | Maleechat Sripipattanakul, Thumwadee Tangsiriwatthana, Sukanda Mahaweerawat |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2561 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 26 |
| Journal No. | 3 |
| Page no. | 198-204 |
| Keyword | unsatisfactory colposcopy, abnormal pap smear, sublingual misoprostol |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 0857-6084 |
| Abstract | Objectives: To assess the effectiveness of 200 ?g sublingual misoprostol for converting an unsatisfactory to satisfactory colposcopic finding.Materials and Methods: Forty-two participants with abnormal cervical cytology and unsatisfactory colposcopic finding who underwent colposcopy between September 2016 and June 2017 were randomized into two groups; either misoprostol or placebo given sublingually. Second colposcopy was performed 2 hours later, and the conversion rate of unsatisfactory to satisfactory colposcopic finding of both groups was analyzed.Results: Baseline characteristics were similar between two groups. Conversion rate of unsatisfactory to satisfactory colposcopic finding in participants who received sublingual misoprostol was statistically significant higher than placebo group (80.9% vs 38.1%, p = 0.011, relative risk = 2.1, 95% confidence interval 1.18-3.80). There was no significant difference in adverse effect between groups.Conclusion: Two hundred micrograms of sublingual misoprostol, 2 hours before performing colposcopy can convert an unsatisfactory finding to a satisfactory one. |
