Factors Associated with Meconium Aspiration Syndrome inCases with Meconium-Stained Amniotic Fluid
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Creator Siriporn Trainak, M.D.
Title Factors Associated with Meconium Aspiration Syndrome inCases with Meconium-Stained Amniotic Fluid
Publisher PIMDEE Co., Ltd.
Publication Year 2559
Journal Title Thai Journal of Obstetrics and Gynaecology
Journal Vol. 24
Journal No. 4
Page no. 240
Keyword Factors, meconium aspiration syndrome, meconium-stained amniotic flid
ISSN 0857-6084
Abstract Objectives: To determine the factors associated with meconium aspiration syndrome (MAS) incases with meconium-stained amniotic flid (MSAF) at Chonburi Hospital.Materials and methods: Singleton pregnancies delivered at Chonburi Hospital with vertex presentationwith MSAF during the 15 May 2011 15 May 2014 period were reviewed. These pregnanciesincluded women who delivered at or beyond 24 weeks of gestation or birth weight at least 700grams but excluded those who delivered infants with lethal congenital abnormalities. They weredivided into 2 groups depending on whether the neonates developed MAS or not. The twogroups were compared retrospectively regarding baseline characteristics, and then binary logisticregression analysis was used to identify independent signifiant factors associated with MAS.Results: Among 776 pregnancies who met the inclusion criteria, 111 neonates developed MAS,665 neonates did not. Thick meconium, abnormal external fetal monitoring, non-vigorousnewborn, Apgar score at 1 minute less than or equal to 7, and low birth weight were signifiantlyassociated with MAS (p<0.05). By the binary logistic regression analysis; thick meconium,non-vigorous newborn, and Apgar score at 1 minute less than or equal to 7 remained statisticallysignifiant (OR 4.82, 95% CI 2.86-8.14, OR 5.87, 95% CI 2.84-12.13 and OR 3.23, 95% CI1.60-6.54, respectively).Conclusion: Thick meconium, non-vigorous newborn and Apgar score at 1 minute less than orequal to 7 were associated with MAS in MSAF
Thai Journal of Obstetrics and Gynaecology

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