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การโคลนยีนตัวรับฮอร์โมนโพรแลคตินในปลาช่อนและศึกษาการแสดงออกในภาวะไฮเปอร์ออสโมติก (Cloning of Snakehead Prolactin Receptor Mrna, Expression during Hyperosmotic Condition) |
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| รหัสดีโอไอ | |
| Creator | ขนิษฐา วิเศษดี |
| Title | การโคลนยีนตัวรับฮอร์โมนโพรแลคตินในปลาช่อนและศึกษาการแสดงออกในภาวะไฮเปอร์ออสโมติก (Cloning of Snakehead Prolactin Receptor Mrna, Expression during Hyperosmotic Condition) |
| Publisher | Genetics Society of Thailand |
| Publication Year | 2556 |
| Journal Title | Thai Journal of Genetics |
| Journal Vol. | S.1 |
| Journal No. | S1 (Special Issue 1) |
| Page no. | 369 |
| Keyword | prolactin, snakehead, shPRLR |
| ISSN | 8578664 |
| Abstract | To investigate the physiological significance of prolactin (PRL) in a snakehead (Channa striata), we cloned and characterized cDNAs encoding its PRL receptor (PRLR) from the gills. The snakehead PRLR cDNA consisted of 2,412 bps and encoded a protein of 618 aa, contained an extracellular domain with 4 cysteins and a WSXWS motif, a single transmembrane domain and intracellular domain with box 1 and box 2 regions. Snakehead PRLR mRNA showed highest expression in gills and kidneys, furthermore, the expression levels in gills were not significant difference between fresh water and salt water. The results suggest that PRL might not be involved in the osmoregulatory organs in snakehead. |
