EFFECTIVENESS OF TEXT MESSAGING VIA APPLICATION LINE ON ADHERENCE TO ANTIRETROVIRAL DRUG AMONG HIV AND AIDS PATIENTS IN KHAOYOI HOSPITAL PHETCHABURI
รหัสดีโอไอ
Creator Namfon Sribundit
Title EFFECTIVENESS OF TEXT MESSAGING VIA APPLICATION LINE ON ADHERENCE TO ANTIRETROVIRAL DRUG AMONG HIV AND AIDS PATIENTS IN KHAOYOI HOSPITAL PHETCHABURI
Contributor Suwalak Suntharapot
Publisher Faculty of pharmacy, Silpakorn University
Publication Year 2565
Journal Title Thai Bulletin of Pharmaceutical Sciences
Journal Vol. 17
Journal No. 2(July-December)2022
Page no. 83-99
Keyword text messaging, LINE application, adherence, antiretroviral drug, HIV, AIDS
URL Website https://li01.tci-thaijo.org/index.php/TBPS
ISSN 2586-8659
Abstract This research aimed to study the effectiveness of text messaging via application LINE on adherence to antiretroviral drug, viral suppression, and CD4 count among HIV and AIDS patients. Thirty-six HIV and AIDS patients who received services and antiretroviral drug at antiretroviral drug clinic Khaoyoi hospital were randomized to intervention (n=18) or control group (n=18). Patients in the intervention group received weekly text messages via the application LINE for 24 weeks and patients can interact and seek advice from a pharmacist. Patients in the control group received standard care from antiretroviral drug clinic. The results were adherence to antiretroviral drug, CD4 levels, viral load suppression, and patient satisfaction. Data were analysed by descriptive and univariate and multivariate with generalized estimating equation. The results of the study found that after 24 weeks of text messaging via application LINE, the mean adherence to antiretroviral drug was higher with statistical significance at week 24 (p<0.001). The mean adherence to antiretroviral drug in the intervention group and the control group was 98.07 ? 2.49 and 85.84 ? 15.41, respectively. CD4 levels was higher with statistical significance (p=0.024). The mean CD4 level in intervention group and the control group was 420.00 ? 153.55 cell/mm3 and 292.78 ? 168.93 cell/mm3, respectively. There were no significant difference in viral suppression between the intervention and control group. An analysis with generalized estimation equations found that text messaging via application LINE could significantly improve adherence to antiretroviral drug and CD4 levels (p=0.001 and 0.037, respectively). Satisfaction with the text messages via the application LINE found that most of the patients rated their satisfaction in the range of 4.20 - 5.00 which is the highest level of satisfaction. Thus, text messaging via application LINE are effective in improving adherence to antiretroviral drug and CD4 count among HIV and AIDS patients. These findings may be of potential benefit for development of HIV and AIDS services.
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