EFFECT OF CHRONIC KIDNEY DISEASE ON WARFARIN USE
รหัสดีโอไอ
Creator Pornwalai Boonmuang
Title EFFECT OF CHRONIC KIDNEY DISEASE ON WARFARIN USE
Contributor Sasimaporn Yaengkratok
Publisher Faculty of pharmacy, Silpakorn University
Publication Year 2563
Journal Title Thai Bulletin of Pharmaceutical Sciences
Journal Vol. 15
Journal No. 2(July-December)2020
Page no. 109-119
Keyword warfarin, chronic kidney disease, bleeding
URL Website https://li01.tci-thaijo.org/index.php/TBPS
ISSN 2586-8659
Abstract Warfarin is an anticoagulant that is used for the prevention of thromboembolism in various indications. The data showed that there was a relation between renal function and warfarin use. Warfarin could reduce thromboembolism and stroke in patients with non-end-stage renal disease. But the efficacy of warfarin decreased in patients with end-stage renal disease with or without renal replacement therapy. In addition, patients with renal insufficiency took risks of bleeding more than patients with normal renal function. The most bleeding occurred via the gastrointestinal tract. Therefore, patients with chronic kidney disease should be closely monitored.
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