EVALUATION OF MEDICATION USE IN PATIENTS WITH CHRONIC HEART FAILURE AT HUA-HIN HOSPITAL
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Creator Pornwalai Boonmuang, Wichai Santimaleeworagun, Wandee Sumret, Lalita Tangkittiwat, Saralee Asavathumrat, Suthinee Suthisripok, Amonnut Manee-in
Title EVALUATION OF MEDICATION USE IN PATIENTS WITH CHRONIC HEART FAILURE AT HUA-HIN HOSPITAL
Publisher Silpakorn University
Publication Year 2561
Journal Title Thai Bulletin of Pharmaceutical Sciences
Journal Vol. 13
Journal No. 2(July-December)
Page no. 163-171
Keyword chronic heart failure, evaluation, guideline recommended treatment
ISSN 1686-9540
Abstract Chronic heart failure has become one of the major health problems in Thailand, due to high mortality rate and excessive medical expenditure. Thus, treatment which is based on guideline recommendations is important. The present study was a retrospective observational study aimed to evaluate medication treatment in chronic heart failure patients with left ventricular ejection fraction less than 40% compared with the guideline recommendations at Hua-Hin Hospital. The data was analyzed by descriptive statistics and chi-square test. Fifty- one chronic heart failure patients with left ventricular ejection fraction less than 40% were included in the study. The results showed that the three most-prescribed medications were loop diuretics (92.2%), beta blockers (56.8%) and ACEIs or ARBs (52.9%), respectively. Moreover, 29.4% of patients used a combination of ACEIs or ARBs and beta blockers. As well, 17.6% of patients were treated with ACEIs or ARBs combined with beta blockers and mineralocorticoid antagonist, which was consistent with guidelines for recommended treatments. In addition, a re-admission rate was lower in the group taking guideline-recommended treatments.
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