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Synthesis, Characterization and In vitro Antibacterial Evaluation of Oxadiazole Derivatives |
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| รหัสดีโอไอ | |
| Creator | Kiran Mehta |
| Title | Synthesis, Characterization and In vitro Antibacterial Evaluation of Oxadiazole Derivatives |
| Publisher | Silpakorn University Research and Development Institute |
| Publication Year | 2560 |
| Journal Title | Silpakorn University Science and Technology Journal |
| Journal Vol. | 11 |
| Journal No. | 1 |
| Page no. | 27-35 |
| Keyword | Oxadiazole, Metal complex, Antibacterial activity |
| ISSN | 2586-842x |
| Abstract | This research paper reports on findings of novel oxadiazole derivatives. Such compounds were prepared and their complexation was performed by treating them with metal salts of Mn (II), Co (II) and Ni (II). The synthesized derivatives were characterized by elemental analysis, IR and electronic spectral studies and magnetic moment studies. Their structures were further confirmed by 1H NMR spectra. The magnetic behaviour and spectroscopic investigation of complexes indicates mononuclear octahedral structures for complexes. All the derivativeswere screened for antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis,Klebsiella pneumonia and Escherichia coli. They showed noticeable antibacterial activity. |
