Major Discordance in the Diagnosis of Osteoporosis Among Participants With Degenerative Lumbar Spine Using Spine and Hip Dual-Energy X-ray Absorptiometry
รหัสดีโอไอ
Creator Alisara Wongsuttilert
Title Major Discordance in the Diagnosis of Osteoporosis Among Participants With Degenerative Lumbar Spine Using Spine and Hip Dual-Energy X-ray Absorptiometry
Contributor Kasem Chaiklongkit, Sutasinee Kongpromsuk, Wanlop Jaidee
Publisher Faculty of Medicine Ramathibodi Hospital, Mahidol University
Publication Year 2561
Journal Title Ramathibodi Medical Journal
Journal Vol. 41
Journal No. 3
Page no. 013-020
Keyword Bone mineral density, DXA, Lumbar spine, Degenerative spine disease
URL Website https://www.tci-thaijo.org/index.php/ramajournal
Website title Ramathibodi Medical Journal
ISSN 0125-3611
Abstract Background: Major T-score discordance in the diagnosis of osteoporosis at spine and the hip may induce misinterpretation in people with degenerative lumbar spine.Objective: To investigate major T-score discordance in the diagnosis of osteoporosis using bone mineral density (BMD) at the lumbar spine and the hip among people with degenerative lumbar spine.Methods: Demographic data, anthropometric measurements, and dual-energy X-ray absorptiometry (DXA) scans at the lumbar spine and the hip were retrieved from a database of Burapha University Hospital. The interrater reliabilities of image interpretation were performed. The correlation between degenerative lumbar spine lesions with T-scores at the lumbar spine and the hip was analyzed. Major discordance was defined when one site is osteoporotic and the other site is osteopenia or normal.Results: Major T-score discordance of the lumbar spine and the hip was 28.6% and the hip BMD detected in participants with osteoporosis was less than the lumbar spine BMD (15.7% vs 36.5%). T-score at lumbar spine showed a false negative rate of 25.0%. Degenerative lumbar spine lesions showed a poor correlation with T-score at the lumbar spine (R2 = 0.21, P < 0.01) and the hip (R2 at femoral neck = 0.24, P < 0.01; R2 at total hip = 0.32, P < 0.01).Conclusions: Twenty-six percent of participants with degenerative lumbar spine were not evaluated L1-L4 BMD. While the hip seems to be the best measurement site, 28.6% of T-score discordance between lumbar spine and hip was still observed. T-score at lumbar spine showed a false negative rate of 25.0% and associated with older age. This study suggested that it would not be suitable to use the hip BMD alone to diagnose osteoporosis in older adults with degenerative spine disease.
รามาธิบดีเวชสาร

บรรณานุกรม

EndNote

APA

Chicago

MLA

ดิจิตอลไฟล์

Digital File
DOI Smart-Search
สวัสดีค่ะ ยินดีให้บริการสอบถาม และสืบค้นข้อมูลตัวระบุวัตถุดิจิทัล (ดีโอไอ) สำนักการวิจัยแห่งชาติ (วช.) ค่ะ