|
Effects of multi-modal exercise and nutritional intervention nursing on microcirculation function and functional recovery in elderly patients with fracture |
|---|---|
| รหัสดีโอไอ | |
| Creator | Ya Su |
| Title | Effects of multi-modal exercise and nutritional intervention nursing on microcirculation function and functional recovery in elderly patients with fracture |
| Publisher | Maejo University |
| Publication Year | 2568 |
| Journal Title | Maejo International Journal of Science and Technology |
| Journal Vol. | 19 |
| Journal No. | 3 |
| Page no. | 208 |
| Keyword | elderly patients with fracture, etoricoxib, multi-modal exercise, nutritional intervention |
| Website title | Maejo International Journal of Science and Technology |
| ISSN | 1905-7873 |
| Abstract | The effects of multi-modal exercise and nutritional intervention combined with etoricoxib on bone metabolism markers and functional recovery in elderly patients with fracture will studied. Eighty elderly patients with fracture admitted to the hospital from April 2023 to April 2024 were selected for the trial. They were randomly divided into group A (n = 40) and group B (n = 40). All patients were given etoricoxib and conventional nursing while group A was also given multi-modal exercise and a structured nutritional intervention (targeting protein, calcium, and vitamin D intake). The bone metabolism markers, functional disability (Oswestry Disability Index), serum matrix metalloproteinase-3 (MMP-3) and cyclooxygenase-2 (COX-2) levels and quality of life were compared between the two groups. Results showed that microvascular blood perfusion and average velocity of blood cell movement levels increased in both groups after the intervention but were significantly higher in group A than in group B. After 1, 2 and 4 weeks of intervention, Oswestry Disability Index scores were lower in group A than in group B. After intervention, serum MMP-3 and COX-2 levels were lower in both groups than before intervention, and lower in group A than in group B. After intervention, all health survey short form scores were higher in both groups than before intervention, with group A being higher than group B (all P < 0.05). Thus, the multi-modal exercise and nutritional intervention combined with etoricoxib have a significant effect on the improvement of bone metabolism markers and functional recovery in elderly fracture patients, while they negatively regulate MMP-3 and COX-2 levels and also improve the quality of life. |
