Two flavonoids first isolated from the seed of Syzygium nervosum and preliminary study of their anticancer and anti-HIV-1 reverse transcriptase activities
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Creator 1. Puttinan Meepowpan
2. Anuruk Chailungka
3. Thiti Junpirom
4. Wilart Pompimon
5. Narong Nuntasaen
Title Two flavonoids first isolated from the seed of Syzygium nervosum and preliminary study of their anticancer and anti-HIV-1 reverse transcriptase activities
Publisher Maejo University
Publication Year 2560
Journal Title Maejo International Journal of Science and Technology
Journal Vol. 11
Journal No. 1
Page no. 58
Keyword 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone,hariganetin,Syzygium nervosum,cytotoxicity,cancer cell lines,anti-HIV-1 reverse transcriptase
ISSN 1905-7873
Abstract Two flavonoids, viz. 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone (DMC) and hariganetin were first isolated from the dichloromethane extract of the seed of Syzygium nervosum and their biological activities against cancer cell lines and HIV-1 reverse transcriptase were preliminary studied. Both DMC and hariganetin show moderate activities against HIV-1 reverse transcriptase with 67.5% and 64.1% inhibition respectively.
MaejoInternational Journal of ScienceandTechnology

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