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Synthesis, characterisation and antimicrobial activities of vic-dioxime derivatives containing heteroaromatic hydrazone groups and their metal complexes |
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| รหัสดีโอไอ | |
| Creator | 1. Halil Biyik 2. Ilknur Babahan 3. Esin Poyrazoglu Coban |
| Title | Synthesis, characterisation and antimicrobial activities of vic-dioxime derivatives containing heteroaromatic hydrazone groups and their metal complexes |
| Publisher | Maejo University |
| Publication Year | 2556 |
| Journal Title | Maejo International Journal of Science and Technology |
| Journal Vol. | 7 |
| Journal No. | 1 |
| Page no. | 26 |
| Keyword | vic-dioximes,hydrazone glyoximes,metal complexes,antimicrobial activity |
| ISSN | 1905-7873 |
| Abstract | Three novel heteroaromatic hydrazone derivatives bearing vic-dioxime groups (L1H2: 5-methyl-2-furfural hydrazone glyoxime, L2H2: 3-acetylpyridine hydrazone glyoxime and L3H2: 4-acetylpyridine hydrazone glyoxime) and their Ni(II), Cu(II) and Co(II) complexes were prepared. They were characterised by elemental analysis, gel permeation chromatography (GPC), FT-IR, UV, 1H NMR and 13C NMR. The antimicrobial activities of compounds L1H2, L2H2, L3H2 and their Ni(II), Cu(II) and Co(II) complexes were evaluated using the disc diffusion method against 13 bacteria and 5 yeasts. The minimal inhibitory concentrations (MICs) against 3 bacteria and 3 yeasts were also determined. Among the test compounds attempted, L1H2, [Co(L1H)2(H2O)2], [Ni(L2H)2], [Cu(L2H)2], L3H2, [Ni(L3H)2 and [Co(L3H)2(H2O)2] showed some activities against certain Gram-positive bacteria and some of the yeasts tested. |
