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Saliva amylase inhibitory property of certain herbs and spices in Lampang, Thailand |
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| รหัสดีโอไอ | |
| Creator | Noppawut Teanprapakun |
| Title | Saliva amylase inhibitory property of certain herbs and spices in Lampang, Thailand |
| Contributor | Napat Thammalungka , Apisara Moolphueng, Jirarat Wongwilai, Pimchanok Mokrid, Sirachat pitakrajpong, Tanongsak Sassa-deepaeng |
| Publisher | Rajamangala University of Technology Lanna, Thailand |
| Publication Year | 2568 |
| Journal Title | Journal of Science and Agricultural Technology |
| Journal Vol. | 6 |
| Journal No. | 1 |
| Page no. | 10-20 |
| Keyword | Plant extract, amylase inhibitor, tannin content, phenolic content |
| URL Website | https://jsat.rmutl.ac.th/ |
| Website title | Journal of Science and Agricultural Technology |
| ISSN | 27301524 |
| Abstract | Salivary ?-amylase inhibitors (SaAIs) derived from spices and herbs have shown promise for the effective management of type 2 diabetes. This study aimed to identify potential SaAIs from aqueous extracts of 15 commonly used plants. Among these, Albizia lebbeck (L.) Benth. exhibited the highest inhibitory activity, followed by Mimosa pudica L., Ipomoea aquatica Forssk., and Gymnema inodorum (Lour.) Decne. Phytochemical analysis indicatedthat A. lebbeck demonstrated the strongest amylase inhibition, which was attributed to its high content of phenolics, flavonoids, tannins, and saponins. M. pudica also showed a significant saponin concentration. I. aquatica displayed notable amylase inhibitory activity linked to its phenolic, flavonoid, and protein content, although it also contained a high amount of reducing sugars. G. inodorum exhibited inhibition through a combination of phenolics, flavonoids,saponins, and proteins. The findings provide compelling evidence that dietary intake of A. lebbeck, I. aquatica, and G. inodorum may positively influence glycemic control. These results suggest that all four plants are promising candidates for further in vivo studies and potential drug development in mammalian models and humans. |