|
Reproductive Performance Comparisons of Three Inbred Mice Strains (BALB/cMlac,C57BL/6Mlac and DBA/2Mlac) at National Laboratory Animal Center, Mahidol University,Thailand |
|---|---|
| รหัสดีโอไอ | |
| Creator | Pornrattana Chumanee;Apisit Laosantisuk;Wanson Keawmanee;Kanchana Kengkoom;Thanaporn Pinpart |
| Title | Reproductive Performance Comparisons of Three Inbred Mice Strains (BALB/cMlac,C57BL/6Mlac and DBA/2Mlac) at National Laboratory Animal Center, Mahidol University,Thailand |
| Publisher | คณะสิ่งแวดล้อมและทรัพยากรศาสตร์ |
| Publication Year | 2557 |
| Journal Title | วารสารการพัฒนางานประจำสู่งานวิจัย |
| Journal Vol. | 1 |
| Journal No. | 1 |
| Page no. | 1 |
| Keyword | Mice;Inbred strains;Reproductive performance;NLAC-MU |
| ISSN | ISSN2392-568X |
| Abstract | Reproductive performance consisting of mean litter size, number of pups that wean (wean: born ratio)and mean reproductive index of three inbred mice strains, which are BALB/cMlac, C57BL/6Mlac andDBA/2Mlac, were investigated to provide some basic information on the breeding and maintaining of a foundation colony. These strains are designated as specific pathogen free animals (SPF) by the NationalLaboratory Animal Center, Mahidol University (NLAC-MU), the organization in which they were housedunder the maximum barrier system. The data from twenty generations of each strain were analyzed by t-test and non-parametric test. The mean litter size (born) values were 4.6?1, 6.2?1.4 and 4.3?1.0, and the wean:born ratios were 0.90?0.1, 0.81?0.2 and 0.83?0.2 for BALB/cMlac, C57BL/6Mlac andDBA/2Mlac, respectively. Furthermore, their mean reproductive indexes were 1.03, 0.94 and 0.71,respectively. Comparison results of the three inbred strains suggested that the reproductive performance of BALB/cMlac is better than that of C57BL/6Mlac and DBA/2Mlac. |