APPLICATION OF ORTHOSIPHON STAMINEUS FOR DIURETIC EFFECT
รหัสดีโอไอ
Creator Janpen Tangjitjareonkun, Waraporn Yahayo, Roongtawan Supabphol
Title APPLICATION OF ORTHOSIPHON STAMINEUS FOR DIURETIC EFFECT
Publisher Faculty of Medicine,Srinakharinwirot University
Publication Year 2560
Journal Title Journal of Medicine and Health Sciences
Journal Vol. 24
Journal No. 1
Page no. 67-78
Keyword Orthosiphon stamineus, diuretic effect, antioxidation, antibateria, urinary tract infection
ISSN 0859-3299
Abstract The most common pharmacological effect of Orthosiphon stamineus predominantly mentioned is a diuretic effect via adenosine receptor leading to the contraction of urinary bladder muscle and relaxation of urethral muscle. Evidence show its safe application in some diseases (1) hypertension; decrease blood pressure and vasoconstriction (2) urinary tract infection; antiinflammatory analgesia antipyretics and antiadhesive activity against uropathognic Escherichia coli to uroepithelial tissue (3) diabetic mellitus; decrease blood glucose due to the a-glucosidase and a-amylase inhibition, and decrease glucotoxicity (4) urolithiasis; increase uric acid excretion, decrease the risk of uric stone formation and kidney injury from calcium oxalate (5) cancer; cytotoxic to many cancer cells and decrease angiogenesis to cancer mass (6) urethral constriction; relaxation of urethral smooth muscle to facilitate urination. Evidence supports the use of Orthosiphon stamineus for diuretic effect and safety for other diseases. That was the reason that traditional medicine mentioned about the application for other diseases. It is worth to consume medicinal plants grown and manufactured in Thailand.
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