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Antioxidant Therapy in Age-related Diseases |
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| รหัสดีโอไอ | |
| Creator | Linda Chularojmontri, Suvara K.Wattanapitayakul |
| Title | Antioxidant Therapy in Age-related Diseases |
| Publisher | Faculty of Medicine,Srinakharinwirot University |
| Publication Year | 2548 |
| Journal Title | Journal of Medicine and Health Sciences |
| Journal Vol. | 13 |
| Journal No. | 1 |
| Page no. | 169-178 |
| ISSN | 0859-3311 |
| Abstract | Aging is associated with mitochondrial dysfunction which may result from oxidativestress.The high level of reactive oxygen species (ROS) contributes, in part, to organdysfunction and pathology of chronic diseases such as cardiovascular disease, diabetes,cancer and Alzheimer's disease.Naturally, cells use endogenous and exogenous antioxidantdefense to keep ROS at harmless level.Oxidative stress occurs when there is unbalancebetween ROS and antioxidant defense.Thus, antioxidants are potentially useful in therapy ofage-related diseases.This review briefly discusses antioxidants that are currently of interest,including superoxide dismutase, coenzyme Q, and alpha-lipoic acid. |
