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Effects of crude medicinal Thai flower extracts on cytotoxicity and FMS-like tyrosine kinase 3 protein expression in EoL-1 leukemic cell line |
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| รหัสดีโอไอ | |
| Creator | 1. Kwanlux Ratnobol 2. Singkome Tima 3. Methee Rungrojsakul 4. Siriporn Okonogi 5. Sawitree Chiampanichayakul 6. Songyot Anuchapreeda |
| Title | Effects of crude medicinal Thai flower extracts on cytotoxicity and FMS-like tyrosine kinase 3 protein expression in EoL-1 leukemic cell line |
| Publisher | Faculty of Associated Medical Sciences, Chiang Mai University |
| Publication Year | 2562 |
| Journal Title | Journal of Associated Medical Sciences |
| Journal Vol. | 52 |
| Journal No. | 1 |
| Page no. | 18-24 |
| Keyword | Thai flowers, crude extracr, leukemia, EoL-1 |
| URL Website | https://www.tci-thaijo.org/index.php/bulletinAMS/index |
| Website title | Journal of Associated Medical Sciences |
| ISSN | 25396056 |
| Abstract | Background: Leukemia is one cause of death worldwide. Nowadays, natural therapies such as the use of medicinal plants may reduce adverse side effects of leukemia. Accordingly, the anticancer properties of medicinal plants have been recognized for centuries. This study focuses on Thai flowers from traditional drug recipes including phikun (Mimusops elengi Linn.), boonark (Mesua ferrea Linn.), ketawa (Gardenia jasminoides J.Ellis), and sarapi (Mammea siamensis(Miq.) T. Anders) for cytotoxicity and leukemia suppression. Fms-like tyrosine kinase 3 (FLT3) is a prognostic marker for acute myeloblastic leukemia (AML) and leukemic cell proliferation. Thus, FLT3 is a reliable marker for minimal residual disease (MRD) assessment in leukemia patients. |
