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MORPHOLOGICAL STUDIES IN THE TREATMENT OF EXPERIMENTAL BURN INJURIES OF THE SECOND AND THIRD DEGREES IN DOGS |
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| รหัสดีโอไอ | |
| Creator | T.N. Shnyakina, N.M. Bezina, N.P. Shcherbakov, L.V. Chernyshova, T.N. Makarova, I.R. Kanagina, L. V. Medvedev? |
| Title | MORPHOLOGICAL STUDIES IN THE TREATMENT OF EXPERIMENTAL BURN INJURIES OF THE SECOND AND THIRD DEGREES IN DOGS |
| Contributor | - |
| Publisher | TuEngr Group |
| Publication Year | 2563 |
| Journal Title | International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies |
| Journal Vol. | 11 |
| Journal No. | 14 |
| Page no. | 11A14H: 1-11 |
| Keyword | Dermis, Thermal burns, Inflammation reaction, Necrosis, Pharmacological mixture, Morphological studies, Regeneration, Granulation tissue. |
| URL Website | http://TuEngr.com/Vol11_14.html |
| Website title | ITJEMAST V11A(14) 2020 @ TuEngr.com |
| ISSN | 2228-9860 |
| Abstract | The article presents the results of morphological studies of an effectiveness method in treatment of burn injuries in dogs using pharmacological mixtures (iodinol-chlorophyllipt solution and vinylin-salicylic liniment), taking into account the phase of the wound process. The composition of the iodinol-chlorophylliptic solution includes iodinol, novocaine, a 1% alcohol solution of chlorophyllipt (diluted 1:5 with distilled water) and dimexide. The composition of the vinylin-salicylic liniment includes salicylic acid, vinylin, a 1% alcohol solution of chlorophyllipt (diluted 1:5 with distilled water) and lavender oil. In the first phase of the wound healing process for the treatment of burns in animals of experimental group No. 2, dressings were used, soaked in iodinol-chlorophylliptic solution, and in the second phase of the wound healing process, a vinylin-salicylic liniment was applied to the burn wound. Morphological studies of burnt tissues showed that in both experimental groups in the early stages of observation, the severity of the exudative phase of the inflammatory reaction is less pronounced than in the control group; the number of macrophages, is higher especially in the experimental group No.2. By the 21st day in experimental group No.2, the specific areas of newly formed collagen fibers and blood vessels with significantly lower cellularity of the infiltrate were greater, which indicates earlier maturation of granulation tissue. From the results, the regeneration of damaged tissues in animals of experimental group No.2 occurred with a predominance of reparative processes. |
