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Cost-outcome of Hepatocellular Carcinoma Screening at Roi-Et Hospital |
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| รหัสดีโอไอ | |
| Creator | Wittaya Roongjangram |
| Title | Cost-outcome of Hepatocellular Carcinoma Screening at Roi-Et Hospital |
| Contributor | Nilawan Upakdee |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2563 |
| Journal Title | Isan Journal ofPharmaceutical Sciences |
| Journal Vol. | 16 |
| Journal No. | 2 |
| Page no. | 21-29 |
| Keyword | Screening, Hepatocellular carcinoma, Cost |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal ofPharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | Hepatocellular carcinoma (HCC) in Thailand was one of leading cause of death. Currently, guidelines for diagnosis and treatment of HCC have advanced. The mortality rate was high because most patients received medical examination when cancer entered late-stage. The screening was more important in finding new cases. Therefore, the study of cost of screening for HCC at the population level will be useful for economic evaluation. Objective: To determine cost and outcome of HCC screening at Roi-Et Hospital. Methods: This is the descriptive study of the HCC screening at Roi-Et Hospital between February 2011 and November 2013. This study measured general characteristics, direct medical costs, outcome of screening from population with positive HBsAg and further screening with physical examination, laboratory examinations and upper abdominal ultrasound. One-way sensitivity analysis was applied to investigate parameter uncertainties. Results: There were 973 positive HBsAg patients received HCC screening with aged 44.10 ? 11.87 years and most of them are domiciled in Roi-Et Province. One hundred twenty patients were detected as positive HBeAg and 4 patients had positive hepatitis C antibody. When the screening was finished, found 9 early-stage HCC patients, 1 late-stage HCC patient and 5 cholangiocarcinoma patients. Total of medical cost was 3,275,044 baht, average medical cost was 3,365.92 baht/visit and average cost of screening per finding a new case of early stage HCC was 363,893.78 baht. Conclusion: HCC Screening could reduce the total cost of HCC treatment. Therefore, considering HCC screening at the population level will lead to early-stage HCC finding that can reduce mortality rate and cost of HCC treatment. |
