10.14456/ijps.2018.32
The Analysis of Modified-Release Drug Trade Names Which are Available in Thailand
รหัสดีโอไอ
10.14456/ijps.2018.32
Creator Sudaporn Thumnu
Title The Analysis of Modified-Release Drug Trade Names Which are Available in Thailand
Contributor Amornrat Boonruang, Surachai Joomprabutra, Thanawadee Preeprem
Publisher Faculty of Pharmaceutical Sciences KKU MSU UBU
Publication Year 2561
Journal Title Isan Journal of Pharmaceutical Sciences
Journal Vol. 14
Journal No. 3
Page no. 140-153
Keyword Immediate-release drugs, Modified-release drugs, Drug trade names
URL Website https://tci-thaijo.org/index.php/IJPS
Website title Isan Journal ofPharmaceutical Sciences, IJPS
ISSN 19050852
Abstract Trade names of pharmaceutical products are used to signify the difference in active ingredients, strengths and drug release characteristics. Modified-release drugs (MRDs) often contain a suffix in the trade name to convey a releasing pattern that differs from the profile of immediate-release drugs or to specify a certain type of modified-release. Common suffixes are words that clearly convey each releasing pattern. The use of uncommon suffixes may cause medication errors. The objectives of this research are to compile a list of trade names of MRDs which are available in Thailand and to analyze if their suffixes agree with the release characteristic of the product. This research aims to raise awareness of various types of modified-release characteristics among health care professionals in order to limit medication errors. Methods: Collect trade names of oral MRDs which are available in Thailand form four public databases: TMT, Monopoly, MIMS Thailand and Orange book. Organize trade names by the patterns of modified-release. Analyze the nomenclature of drug trade names and compare the meaning of their suffixes with the release characteristic of the product. Summarize the features of MRD trade names that are sold in Thailand and their availability in the National List of Essential Medicine (NLEM). Results: Oral MRDs that are sold in Thailand comprise of 1,053 trade names, 609 items (58 %) are in the NLEM. Most therapeutic categories of NLEM include MRDs, but MRDs are most used in the treatment of central nervous system disorders. In general, the trade names of MRDs that are available in Thailand often fail to provide appropriate clues for drug releasing profiles. Among 1,053 trade names, only 32% contain suffixes (23% with common suffixes and 9% with uncommon suffixes) and 68% do not use any suffixes. Conclusion: Most MRDs use trade names that do not contain any suffixes or use some that lack of standard. This naming practice may create confusion among healthcare providers and potentially develop into medication error events. The compiled list of MRDs is available at https://gg.gg/mrd-thailand.
Faculty of Pharmaceutical Sciences, Khon Kaen University

บรรณานุกรม

EndNote

APA

Chicago

MLA

ดิจิตอลไฟล์

Digital File
DOI Smart-Search
สวัสดีค่ะ ยินดีให้บริการสอบถาม และสืบค้นข้อมูลตัวระบุวัตถุดิจิทัล (ดีโอไอ) สำนักการวิจัยแห่งชาติ (วช.) ค่ะ