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Effect of Lactobacillus brevis on Skin Tissue Repair: Antioxidative Effect, Anti-collagenase and Stimulation of Fibroblast Cell Proliferation |
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| รหัสดีโอไอ | |
| Creator | Pinchapat Thanasanwanich |
| Title | Effect of Lactobacillus brevis on Skin Tissue Repair: Antioxidative Effect, Anti-collagenase and Stimulation of Fibroblast Cell Proliferation |
| Contributor | Supatra Porasuphatana |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2557 |
| Journal Title | Isan Journal ofPharmaceutical Sciences |
| Journal Vol. | 10 |
| Journal No. | 3 |
| Page no. | 295-306 |
| Keyword | Lactobacillus brevis, antioxidant activity, anti-collagenase activity, fibroblast proliferation |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal ofPharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | Lactobacillus sp, a probiotic bacteria, has long been used for health promotion purposes. This study aimed to investigate factors that affect proliferation phase of skin tissue repair by cell and cellular components of Lactobacillus brevis. Result showed increase significance different antioxidant activityby FRAP and ABTS technique for intact cell and intracellular cell free extract 109cfu/ml. Anti-collagenase activity result showed extracellular extract exhibited the highest anti-collagenase activity at 57.10?14.60%. For stimulation of fibroblast proliferation, intracellular cell free extract demonstrated the tendency to increase fibroblast proliferation as determined by MTT method and extracellular extract showed a significant increase in fibroblast proliferation. This study, therefore, showed antioxidant activity of L. brevis as well as anti-collagenase activity and cell proliferative effect which could be beneficial for the advanced knowledge in the development of skin products from L. brevis to be used for skin care. |
