Outcome of In-depth Pharmaceutical Care to Quality of Life and Clinical Outcome in Uncontrolled Asthma Patients
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Creator Noppawan Siripan
Title Outcome of In-depth Pharmaceutical Care to Quality of Life and Clinical Outcome in Uncontrolled Asthma Patients
Contributor Parimoke Kerdchantuk, Sunee Lertsinudom
Publisher Faculty of Pharmaceutical Sciences KKU MSU UBU
Publication Year 2556
Journal Title Isan Journal ofPharmaceutical Sciences
Journal Vol. 9
Journal No. 2
Page no. 12-22
Keyword Asthma, Pharmacist's intervention, Pharmaceutical care
URL Website https://tci-thaijo.org/index.php/IJPS
Website title Isan Journal ofPharmaceutical Sciences, IJPS
ISSN 19050852
Abstract Introduction: The Asthma Clinic at Banphai Hospital was established in 2004. However, the majority of the patients were found to be suffering from uncontrolled asthma. Therefore, a new approach to service in the Asthma Clinic was found to be necessary. Materials and Method: The study is evaluate the quality of life and clinical outcome before and after in-depth pharmaceutical care of patients with uncontrolled asthma. The study, through a pretest-posttest experimental design was carried on a group patients over the age of 15 years, who for at least the past 6 months had an uncontrolled level of asthma as per the 2009 guidelines of the Global Initiative for Asthma (GINA). Patients participating in the study were given an in-depth pharmaceutical care depending on a patient's individual needs. Clinical outcome were measured every 2 months and patients with continued uncontrolled asthma were visited at home by a multidisciplinary team within 7 days for further care for the next six month period. Quality of Life was measured using the MiniAsthma Quality of Life Questionnaire (MiniAQLQ), Thai version. Results: A total of 46 patients were recruited, mostly female (58.7%), majority non-smoking (71.7%), and mean age 59.4 years. After in-depth pharmaceutical care, the overall average quality of life was increased from 4.00 ? 0.95 to 5.04 ? 0.88 points (p<0.001) and increased significantly in every dimension; the number of uncontrolled asthmatic patients decreased from 46 (100%) to 19 patients (41.3%) (p<0.001), the average lung function as measured by PEFR increased from 58.5 ?23.3% to 66.2?24.3% (p<0.001), and the of patients who visited the emergency department and/or had hospital admission was decreased (p=0.439 and p=0.317 respectively). Conclusion: The in-depth pharmaceutical care to uncontrolled asthmatic patients can improve the quality of life and clinical outcome.
Faculty of Pharmaceutical Sciences, Khon Kaen University

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