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Bioaccessibility of Aflatoxin B? in Grinded Corn and Peanut by in vitro Digestion Model |
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| รหัสดีโอไอ | |
| Creator | Witchada Simla |
| Title | Bioaccessibility of Aflatoxin B? in Grinded Corn and Peanut by in vitro Digestion Model |
| Contributor | Supatra Porasuphatana, Piyada Songsermsakul |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2552 |
| Journal Title | Isan Journal ofPharmaceutical Sciences |
| Journal Vol. | 5 |
| Journal No. | 2 |
| Page no. | 108-113 |
| Keyword | AFB, bioaccessibility, in vitro digestion |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal ofPharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | Aflatoxin B? (AFB?) is a secondary metabolite produced principally by Aspergillus flavus and Aspergillus Parasiticus. This toxin represents a significant health hazard for those exposed to it continually for a prolonged period. Aflatoxigenic molds are commonly found in corn and peanuts, and under certain conditions aflatoxins will be formed. In vitro digestion is a method that has been used to estimate the bioaccessibility of chemicals and contaminants in foods. An in vitro digestion experiment was carried out in this study to analyze the bioaccessibility of AFB? in grinded corn and peanut. Trifluoroacetic acid-derivatized AFB? was measured using a HPLC-fluorescent detector. Results indicated that the bioaccessibility of AFB? in grinded corn and peanut was relatively high at 95% 94%, respectively. When AFB?-contaminated grinded corn and peanut are ingested, most of the AFB? will be dissolved into chyme, with this strongly influencing the bioavailability of AFB? in humans. This may have important implications on dietary exposure. Findings from the current study could be applied to improve risk assessment of ingested AFB?. |
