Development of Eugenia grataExtract Film Strip for Oral Hygiene
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Creator Wandee Rungseevijitprapa
Title Development of Eugenia grataExtract Film Strip for Oral Hygiene
Contributor Chutinun Prasitpuriprecha
Publisher Faculty of Pharmaceutical Sciences KKU MSU UBU
Publication Year 2550
Journal Title Isan Journal ofPharmaceutical Sciences
Journal Vol. 3
Journal No. 1
Page no. 17-24
Keyword Film strip, Eugenia grata, oral hygiene, antimicrobial activity, Staphylococcus aureus, Streptococcus faecalis, Bacillus subtilis
URL Website https://tci-thaijo.org/index.php/IJPS
Website title Isan Journal ofPharmaceutical Sciences, IJPS
ISSN 19050852
Abstract The purposes of this study were to develop polymeric film strips containing Eugenia grataextract with good physical characteristics (optimal thickness, easily peel from teflon plate and optimal fragility, strength, clarity and fast dissolution) and to test the activity of film strip containing E. grataagainst pathogenic bacteria in oral cavity using Disc-diffusion assay. The selected oral film strip consisted of 5% tacca : 5% pectin : 1.5% HPMC : 0.25% glycerin in the proportion of 1:1:1:0.25. The 5 mg/ml (double concentration of Minimum inhibitory concentration, MIC) E. grataextracts film strip inhibited Staphylococcus aureus, Streptococcus faecalis and Bacillus subtiliswith Inhibition zone of 9, 12 and 11 mm, respectively while the commercial film strip inhibited only B. subtilis.In conclusion, the film strip with E. grataextracts could effectively inhibit microbial growth in oral cavity and should be developed for commercial oral hygienic product.
Faculty of Pharmaceutical Sciences, Khon Kaen University

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