Optimization of ultrasonic-assisted extraction for monacolin K, antioxidant activity, pigment and citrinin of monascal waxy corn by response surface methodology
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Creator Kitisart Kraboun, Worasit Tochampa, Nitipong Jittrepotch, Kamonwan Rojsuntornkitti, Wassana Chatdamrong and Teeraporn Kongbangkerd
Title Optimization of ultrasonic-assisted extraction for monacolin K, antioxidant activity, pigment and citrinin of monascal waxy corn by response surface methodology
Publisher Faculty of Agro-Industry
Publication Year 2560
Journal Title Food and Applied Bioscience
Journal Vol. 5
Journal No. 2
Page no. 115-131
Keyword Optimization,Ultrasonic, Monacolin K, Monascal waxy corn,Response surface methodology
URL Website www.tci-thaijo.org/index.php/fabjournal
Website title www.tci-thaijo.org/index.php/fabjournal/article/view/80267
ISSN 2286-8615
Abstract This study aims to investigate the ultrasonic extraction optimization of monascal waxy corn (MWC). An optimization procedure using a central composition design with two factors (ethanol concentration and temperature) consisting of 13experimental runs with five replicates of the central points was applied and a second-order polynomial model was used to describe the effects of these parameters on extraction for monacolin K content, antioxidant activities, pigment intensity and citrinin content. The optimized conditions were 69.91% ethanol/49.95?C (monacolin K); 69.62% ethanol/49.15?C (DPPH); 70.67%ethanol/ 49.90?C (chelating ability on Fe2+); 70.91% ethanol/50.80oC (Pigment); 85.00% ethanol/60oC (citrinin) with corresponding yields of 348.72 mg/kg dry weight; 2.65 mmol Trolox/ml; 96.76%; 4072.45 unit/g dry weight and 2.04 ?g/kg dry weight, respectively. The maximalmonacolin K content predictedbyresponse surface analysis was349.59 mg/kg dry weight. Theexperimental value was closeto those predicted values, showing fitting of the model (R2= 0.924) applying RSM for optimizing the ethanol concentration and temperature on monacolin K content from MWC.
Chiang Mai University

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