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Association between Blood Lead Levels and Cognitive Function among Adults in Thai Communities |
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| รหัสดีโอไอ | |
| Creator | Parichat Ong-Artborirak |
| Title | Association between Blood Lead Levels and Cognitive Function among Adults in Thai Communities |
| Contributor | Yanankamon Napatphosri, Titaporn Luangwilai, Parichat Ong-Artborirak |
| Publisher | Thai Society of Higher Education Institutes on Environment |
| Publication Year | 2569 |
| Journal Title | EnvironmentAsia |
| Journal Vol. | 19 |
| Journal No. | 1 |
| Page no. | 44-53 |
| Keyword | Lead exposure, Blood lead level, Cognitive impairment, MoCA |
| URL Website | http://www.tshe.org/ea/index.html |
| Website title | EnvironmentAsia |
| ISSN | 1906-1714 |
| Abstract | Lead exposure, both direct and indirect, may contribute to cognitive impairment. This study examined the relationship between lead exposure and cognitive function among Thai adults. A cross-sectional study was conducted with 139 participants aged over 50 in Samut Prakan Province, whose exposure originated from environmental or informal occupational pathways. Data were collected through interviewer-administered questionnaires, the Thai version of the Montreal Cognitive Assessment (MoCA) to assess cognitive function, and venous blood sampling to determine blood lead level. The overall mean MoCA score was 20.7. When participants were stratified by lead exposure levels into high (≥ 3 μg/dL) and low (< 3 μg/dL) groups, the mean MoCA scores differed significantly (19.0 vs. 21.1 points; p = 0.021). Multiple linear regression showed that individuals in the high-exposure group had MoCA scores approximately 1.8 points lower than those in the low-exposure group, after adjusting for sex, age, education level, perceived financial status, body mass index, smoking, and alcohol consumption (B = –1.8, p = 0.040), indicating cognitive decline. Even low-level lead exposure from environmental and occupational sources may increase the risk of cognitive impairment. These findings highlight the need for surveillance and preventive measures in at-risk populations. |
