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Effect of Copper Concentration on Lead and Cadmium Bioavailability in Children Age 9 to 15-Year-Old in Zinc Contaminated Areas |
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| รหัสดีโอไอ | |
| Creator | 1. Tippawan Chaiwong 2. Pramote Loeskhampom 3. Sanhawat Chaiwong |
| Title | Effect of Copper Concentration on Lead and Cadmium Bioavailability in Children Age 9 to 15-Year-Old in Zinc Contaminated Areas |
| Publisher | Thai Society of Higher Education Institutes on Environment |
| Publication Year | 2563 |
| Journal Title | EnvironmentAsia |
| Journal Vol. | 13 |
| Journal No. | 3 |
| Page no. | 26-35 |
| Keyword | Trace elements, Lead and cadmium bioavailability, Age 9-15 years old, Tak, Zinc mining |
| URL Website | http://www.tshe.org/ea/index.html |
| Website title | EnvironmentAsia |
| ISSN | 1906-1714 |
| Abstract | This study determined the levels of specific trace elements in the urine of children aged 9 - 15 years old in zinc-contaminated areas and studied the simultaneous presence of certain elements influenced the bioavailability of lead and cadmium. Urine samples of 736 children living in three sub-districts of Tak province, including Prathadpadeang, Mae Tao, and Mae Ku, were investigated with inductively coupled plasma mass spectrometry to determine levels of zinc (Zn), copper (Cu), iron (Fe), lead (Pb), and cadmium (Cd). The results showed that 43.0% of children lived in Mae Tao sub-district. The body weight of the subjects at birth was < 3,000 grams, and they were underweight as per body mass index. The differencein Cd level in urine (UCd) between 13-15 years old and 9-12 years old was statistically significant. Furthermore, statistically significant differences were observed in levels of Cu level in urine (UCu) and Pb level in urine (UPb) based on the gender of the subjects. UCd and UPb levels were higher compared to other trace elements in older children and female/male (SRM 2670:NIST). In contrast, UCu and UZn levels were low. Stepwise regression analyses indicated that Cu concentration was a dominant factor influencing the availability of Pb (r square = 0.25) and Cd (r square = 0.16) in human body as follows: Lead availability = 0.295 + 0.304 Cu + 0.256 Fe + 152 Zn, Cadmium availability = 0.050 - 0.079 Cu + 0.057 Fe + 0.395 Zn. Our study concluded that Cu levels were low in children aged 9-15 years old, which could have led to accumulation of Cd and Pb in their bodies. |
