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Curcumin: a Polyphenol with Molecular Targets for Cancer Control |
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| รหัสดีโอไอ | |
| Creator | Muhammad Imran Qadir, Syeda Tahira Qousain Naqvi, Syed Aun Muhammad |
| Title | Curcumin: a Polyphenol with Molecular Targets for Cancer Control |
| Publisher | APJCP |
| Publication Year | 2559 |
| Journal Title | Asian Pacific Journal of Cancer Prevention |
| Journal Vol. | 17 |
| Journal No. | 6 |
| Page no. | 2735-2739 |
| Keyword | Curcumin, cancer, molecular targets of curcumin |
| Abstract | Curcumin, is a polyphenol from Curcuma longa (turmeric plant), is a polyphenol that belongs to the ginger family which has long been used in Ayurveda medicines to treat various diseases such as asthma, anorexia, coughing, hepatic diseases, diabetes, heart diseases, wound healing and Alzheimers. Various studies have shown that curcumin has anti-infectious, anti-inflammatory, anti-oxidant, hepatoprotective, thrombosuppressive, cardio protective, anti-arthritic, chemo preventive and anti-carcinogenic activities. It may suppress both initiation and progression stages of cancer. Anticancer activity of curcumin is due to negative regulation of inflammatory cytokines, transcription factors, protein kinases, reactive oxygen species (ROS) and oncogenes. This review focuses on the different targets of curcumin to treat cancer. |
