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Efficacy and Safety of Laser Surgery and Transurethral Resection of the Prostate for Treating Benign Prostate Hyperplasia: a Network Meta-analysis |
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| รหัสดีโอไอ | |
| Creator | 1. Li Wang 2. Qiu-Yan Yu; Yan Liu; Zhen-Li Zhu; Yuan-Wei Huang; Ke Li |
| Title | Efficacy and Safety of Laser Surgery and Transurethral Resection of the Prostate for Treating Benign Prostate Hyperplasia: a Network Meta-analysis |
| Publisher | APJCP |
| Publication Year | 2559 |
| Journal Title | Asian Pacific Journal of Cancer Prevention |
| Journal Vol. | 17 |
| Journal No. | 9 |
| Page no. | 4281-4288 |
| Keyword | TURP; BPH; laser surgery; meta-analysis |
| Abstract | Background: Traditional meta-analyses or systematic reviews of randomized controlled trials (RCTs) have been used to compare laser surgeries and transurethral resection of the prostate (TURP) for benign prostate hyperplasia (BHP), but they cannot provide a hierarchy regarding ef cacy and safety of treatment. Objective: We therefore performed a network meta-analysis (NMA) to compare and create hierarchies for ef cacy and safety of TUPR and laser surgeries for BPH. Materials and Methods: We searched for reports of RCTs published up to April 25, 2015. After methodological quality assessment and data extraction, we performed an NMA to compare TURP and laser surgeries for BPH. Results: We ranked the treatments of TURP and laser surgeries for BPH. For IPSS at 6 months, holmium laser resection of the prostate (HoLRP) ranked the rst-best and at 12 months, holmium laser enucleation of the prostate (HoLEP). For Qmax at 6 and 12 months, HoLEP ranked the rst-best; for operative time it was TURP; for cathedral removal time, diode laser enucleation of the prostate (DiLEP) ranked the rst-best. Conclusions: Although TURP is considered the gold standard for treating BPH, it is not better in terms of ef cacy and safety compared with the laser surgery. Our NMA created hierarchies for the 9 types of surgery in terms of ef cacy and safety, which should help clinicians choose the best approach for the individual patient. |
