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Colorectal Cancer Mortality in Shiraz, Iran |
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| Creator | 1. Mostafa Dianatinasab 2. Haleh Ghaem; Abbas Rezaianzadeh; Seysd Vahid Hosseini; Hajar Khazraei |
| Title | Colorectal Cancer Mortality in Shiraz, Iran |
| Publisher | APJCP |
| Publication Year | 2559 |
| Journal Title | Asian Pacific Journal of Cancer Prevention |
| Journal Vol. | 17 |
| Journal No. | 8 |
| Page no. | 4101-4105 |
| Keyword | Mortality ; survival rate ; colorectal cancer ; Cox regression ; Iran |
| Abstract | Background: Mortality among Iranian patients with colorectal cancer has not been fully examined and the factors associated with their survival are still controversial. This study aimed to determine the mortality rate and its related factors among the patients with colorectal cancer in southwestern regions in Iran. Materials and Methods: This prospective cohort study was conducted on 220 patients with colorectal cancer referred to Fahighi Hospital, Shiraz, Iran from 2009 to 2014. Data were collected from the patients๊ medical records and were analyzed using Cox regression analysis. Results: Over a median follow-up of 29.3 months, 56 out of the 220 patients (25.5%) died, 32 (14.5%) aged below 40 years, and 45.5% were female. Based on the results of multiple Cox regression analysis, family history of gastrointestinal cancer, stage III, former smoking, type of lesion (fungative and polypoid), and opium use were associated with a greater risk of colorectal cancer mortality (all P<0.05). Conclusions: This cohort study found that the mortality rate of colorectal cancer in Iran is lower than that in European countries. In addition, behavioral and clinical factors were signi cantly associated with the survival rate. Addressing the related factors would help healthcare providers and physicians provide the best care and improve the survival rate. |
