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10-oxo-cis-12-octadecenoic acid produced by selected lactic acid bacteria with probiotic capability |
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| รหัสดีโอไอ | |
| Title | 10-oxo-cis-12-octadecenoic acid produced by selected lactic acid bacteria with probiotic capability |
| Creator | Le Nu Anh Thu |
| Contributor | Shigenobu Kishino, Yoshie Uchibori, Yasunori Yonejima, Jun Ogawa |
| Publisher | Mahasarakham University |
| Publication Year | 2558 |
| Keyword | 10-Hydroxy-cis-12-octadecenoic acid, Lactic acid bacteria, Linoleic acid, 10-oxo-cis-12-octadecenoic acid, Lactobacillus brevisM003 |
| Abstract | Probiotics with ability to produce 10-oxo-cis-12-octadecenoic acid (KetoA) have been considered to be beneficial for human health with its known role in activating the fatty acids oxidation and reducing the triglyceride synthesis in white adipose tissue. Through the screening of about500 strains of lactic acid bacteria, Lactobacillus brevisM003 was selected as a potential probiotic for KetoA production. By analyzing the cultivation and reaction conditions to obtainthe probiotic cells with high KetoA-producing activity, theM003 bacterial cells in the exponential growth phase without inducers showed the significant production of KetoA (approximately 0.03 mg/mL). |
