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Bioactive compounds from dendrobium infundibulum |
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| รหัสดีโอไอ | |
| Title | Bioactive compounds from dendrobium infundibulum |
| Creator | Salinee Na Ranong |
| Contributor | Boonchoo Sritularak, Kittisak Likhitwitayawuid |
| Publisher | Chulalongkorn University |
| Publication Year | 2560 |
| Keyword | Bioactive compounds, Dendrobium infundibulum (Orchidaceae), สารออกฤทธิ์ทางชีวภาพ, เอื้องตาเหิน |
| Abstract | Phytochemical study of the methanol extract from Dendrobium infundibulum (Orchidaceae) led to isolation of nine pure compounds including two new compounds (dendroinfundin A and dendroinfundin B) and seven known compounds (ephemeranthol A, moscatilin, aloifol I, batatasin III, 3,3'-dihydroxy-4,5-dimethoxybibenzyl, 3,4'-dihydroxy-3',4,5-trimethoxybibenzyl and dendrosinen B). Their structures were determined from their spectroscopic data. All compounds were then examined for their lipase and alpha-glucosidase inhibitory activities. Dendrosinen B (IC50 = 295.0±37.9 µM) showed moderate inhibitory activity against lipase when compared with orlistat (IC50 = 31.4±0.6 nM). Strong anti alpha-glucosidase agents were batatasin III (IC50 = 148.8±8.4 µM) and dendrosinen B (IC50 = 213.9±2.4 µM), which were more potent than acarbose (IC50 = 809.1±22.2 µM). |
| URL Website | cuir.car.chula.ac.th |
