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Novel collagen-alginate beads with long-lasting curcuminoids encapsulation |
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| รหัสดีโอไอ | |
| Title | Novel collagen-alginate beads with long-lasting curcuminoids encapsulation |
| Creator | Preeyanuch Sasiwilassakorn |
| Contributor | Pattara Thiraphibundet |
| Publisher | Chulalongkorn University |
| Publication Year | 2557 |
| Keyword | Alginates, Collagen, อัลจิเนต, คอลลาเจน |
| Abstract | New collagen-alginate coated beads (col-alg coated beads) were successfully prepared by using transacrylation reaction between ester group of propylene glycol alginate and amino group of collagen. The coated beads prepared by 10% collagen had resulted in the good sphere shape with diameter of 5.20 mm. The hardness of the coated beads were found to decrease when increase the collagen concentration. The new amide bond of the outer membrane was proved by the Light microscopy, FTIR and DSC results. Two types of curcuminoid were loaded in the beads which were free curcuminoid and Cur-loaded EC particles. Cur-loaded EC particles showed slower releasing than free curcuminoid in pH 5.5 buffer. Furthermore, the outer membrane of col-alg coated beads can retarded the release of curcuminoid. |
| URL Website | cuir.car.chula.ac.th |
