Nanospheres from UV-absorbing chitosan derivatives
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Title Nanospheres from UV-absorbing chitosan derivatives
Creator Pimsiree Deemak
Contributor Supason Wanichwecharungruang, Rath Pichyangkura
Publisher จุฬาลงกรณ์มหาวิทยาลัย
Publication Year 2552
Keyword Chitosan, Light absorption, ไคโตแซน, การดูดกลืนแสง
Abstract In this work, four groups of UV-absorbing chitosan derivatives were synthesized. They include 1) UVB filter cinnamoylchitosan (CC) 2) UVA filter 2,4,5-trimethoxycinnamoylchitosan (245CC) 3) UVA filter 4-hydroxy-3-methoxycina malidene succinylchitosan (43CSC) and 4) UVB filter 2,4-dimethoxybenzalidenesuc cinylchitosan (24BSC). Fabrication of nanoparticles from the obtained derivatives was carried out by solvent displacement method. It was found that the size of the particles varied with degree of cinnamoyl substitution. 2,4,5-Trimethoxycinnamoyl chitosan and 2,4-dimethoxybenza lidenesuccinylchitosan are more photostable than cinnamoylchitosan and 4-hydroxy-3-methoxycinnamalidenesuccinylchitosan, respectively. In addition, 2,4-dimethoxybenzalidenesuccinylchitosan possess similar UVB filtering efficiency to the popularly used UVB filter 2-ethylhexyl-4- methoxycinnamate.
URL Website cuir.car.chula.ac.th
Chulalongkorn University

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