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The Cut-Off Value of HbA1c for Prediabetes and Diabetes among Obese Children and Adolescents |
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| รหัสดีโอไอ | |
| Creator | 1. Thanyaros Sinsophonphap 2. Khansatit Thavornsawadi |
| Title | The Cut-Off Value of HbA1c for Prediabetes and Diabetes among Obese Children and Adolescents |
| Publisher | Text and Journal Publication |
| Publication Year | 2565 |
| Journal Title | Vajira Medical Journal |
| Journal Vol. | 66 |
| Journal No. | 4 |
| Page no. | 299-310 |
| Keyword | prediabetes, diabetes, oral glucose tolerance test, childhood obesity |
| URL Website | https://tci-thaijo.org/index.php/VMED |
| Website title | Vajira Medical Journal (วชิรเวชสาร) |
| ISSN | 0125-1252 |
| Abstract | Objective: To determine the optimal cut-off value of HbA1C for prediction of prediabetes and diabetes among obese children and adolescents age 1015 years at Faculty of Medicine Vajira Hospital. Methods: A cross-sectional descriptive study has been performed in 230 participants between 10-15 years old who underwent an OGTT in 2015-2020. The diagnostic performance of HbA1c for prediabetes and diabetes was determined using the area under the Receiver operating characteristic curve. Results: The prevalence of prediabetes and diabetes was 35.2% and 3.1%, respectively. The kappa coefficient for agreement between OGTT and HbA1c was 87.07%. The optimal HbA1c cut-off value were ? 5.5 (AUC, 0.565; a sensitivity of 65.4% and a specificity of 45.1%) for prediabetes and ? 6.6 (AUC, 0.644; a sensitivity of 42.9% and specificity of 99.1%) for diabetes. Conclusion: HbA1c has low sensitivity and specificity for diagnose prediabetes. HbA1c has low sensitivity but high specificity for predicting diabetes in Thai children and adolescents. |
