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Survival Rate of Renal Replacement Therapy Patients in Charoenkrung Pracharak Hospital |
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| รหัสดีโอไอ | |
| Creator | Kamonrat Chongthanakorn |
| Title | Survival Rate of Renal Replacement Therapy Patients in Charoenkrung Pracharak Hospital |
| Publisher | Text and Journal Publication |
| Publication Year | 2561 |
| Journal Title | Vajira Medical Journal |
| Journal Vol. | 62 |
| Journal No. | 1 |
| Keyword | hemodialysis, continuous ambulatory peritoneal dialysis, survival analysis, dialysis modality |
| URL Website | https://tci-thaijo.org/index.php/VMED |
| Website title | Vajira Medical Journal (วชิรเวชสาร) |
| ISSN | 0125-1252 |
| Abstract | Objective: This study aimed to analyze survival data and the factors associated with treatment outcomes in end-stage renal disease (ESRD) patients. Methods: This was a retrospective analysis of survival data in a single-center cohort of 337 ESRD patients between 2009 and 2015. The database of medical records such as baseline demographics, comorbidities and mortality data were analyzed by cox-regression analysis and Kaplan-Meier analysis. Results: One hundred seventy-four (51.6%) patients were male and 163 (48.4%) patients were female. 181(53.7%) patients were on continuous ambulatory peritoneal dialysis (CAPD), 156 (36.3%) patients were on hemodialysis (HD), 153 (45.4%) patients started renal replacement therapy (RRT) at eGFRs between 3.01-5.99 cc/min/m2, 130 (38.6%) patients started RRT at eGFR more than 6 cc/min/m2, and 54 (16%) patients started RRT at eGFR below 3 cc/min/m2. As for laboratory results, hematocrit level was 29 ? 5.4%, serum calcium was 8.7 ? 1.3 mg/dL, serum phosphate was 4.5 ? 2.8 mg/dL, and intact parathyroid was 464.4 ? 556.8 pg/mL. The average duration of treatment in HD patients (773.8 ? 544.8 days) was statistically significantly higher than the average duration of treatment in CAPD patients (567.5 ? 556.8 days); the risk of death was higher in patients initiating dialysis with CAPD than those initiating dialysis with HD (hazard ratio (HR) = 7.86; 95% confidence interval (CI) 2.5621.13; p<0.001). Patients over 60 years old had a higher risk of death compared to those younger than 60 (HR = 3.32; 95% CI 1.23-8.91; p<0.05). Conclusion: ESRD patients, initiating dialysis with HD had better survival outcomes than those initiating dialysis with CAPD. These findings were potentially confounded by many factors. Randomized controlled trials should be conducted as well as matching in subjects should be carried out to answer this question. |
