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Organophosphates and Development of Infants |
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| รหัสดีโอไอ | |
| Creator | 1. Boonsita Suwannakul 2. Krongporn Ongprasert 3. Ratana Sapbamrer |
| Title | Organophosphates and Development of Infants |
| Publisher | Text and Journal Publication |
| Publication Year | 2561 |
| Journal Title | Vajira Medical Journal |
| Journal Vol. | 62 |
| Journal No. | 5 |
| Keyword | Organophosphates, development, infants, pesticides |
| URL Website | https://tci-thaijo.org/index.php/VMED |
| Website title | Vajira Medical Journal (วชิรเวชสาร) |
| ISSN | 0125-1252 |
| Abstract | Abstract Organophosphates insecticides are used worldwide in an agricultural sector. These chemicals can cause acute and chronic neurotoxicity in humans. Regarding vulnerable population, such as pregnant women and children, organophosphates can transfer from mothers to children through placenta and breast milk, resulting in adverse effects on growth and development of children. Furthermore, exposure to low levels of organophosphates during infant period might cause adverse effects on child development because brain develops rapidly in this period. Thus, this review article aims to review (1) toxic mechanism of organophosphates on nervous system; (2) brain and nervous system development; (3) tools forevaluating developmentof infants; (4)effectsoforganophosphates on development of infants (0 - 12 months). From literature review during 2006 - 2017, there were 7 articles studying the association between prenatal exposure to organophosphates and infant development. Of the7articles,5articles revealed theassociation betweenhistoryofexposure to organophosphate and infant development while 2 articles found no association. Prevention of prenatal exposure to chemicals and evaluation of development in risk infant groups such as infants in agricultural area, are the important timing to cure and stimulate infants' development promptly. |
