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Survival Analysis of Time to Amputation Event Data in Patients with Severe Foot Problems in Vascular Practice |
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| รหัสดีโอไอ | |
| Creator | 1. Sumittra Muangkhoua 2. Prasong Kitidamrongsuk 3. Chukiat Viwatwongkasem 4. Waigoon Stapanavatr |
| Title | Survival Analysis of Time to Amputation Event Data in Patients with Severe Foot Problems in Vascular Practice |
| Publisher | Faculty of Medicine Vajira Hospital |
| Publication Year | 2559 |
| Journal Title | Vajira Med J |
| Journal Vol. | 60 |
| Journal No. | 3 |
| Page no. | 159 - 170 |
| Keyword | Time to event analysis, Amputation, Severe foot problems, Vascular practice |
| ISSN | 0125-1252 |
| Abstract | Objective: To estimate time to amputation event in patients with severe foot problems in vascular practice and investigate the relationship of factors influencing the amputation event and time of patients with severe foot problems in vascular practice.Methods: The study design was a retrospective cohort study using data collected from medical records in the Faculty of Medicine Vajira Hospital, Navamindradhiraj University. The study included patients who were diagnosed with patients with severe foot problems in vascular practice (patients who were diagnosed with critical limb ischemia (CLI) and/or diabetic foot) between January 1, 2009 and December 31, 2010, and follow-up times started from January 1, 2009 to December 31, 2014.Results: There were 372 patients, the follow-up time ranged from 0.066 to 72.933 months (median 50.466 months). There were detected amputation event in 89 of 372 patients (23.9%). The 10th percentiles were 1.66 months. According to Cox's proportional hazard model, there were 3 significant variables affecting the amputation event rates, that were smoking, HbA1c ? 7.5% and presence of renal disease (p-value = 0.034, <0.0001 and 0.021, respectively).Conclusion: In vascular practice, patients with severe foot problems who smoked, had HbA1c ? 7.5% and had renal disease were more prone to have amputation events. |
