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Rare paraneoplastic aplastic anemia in malignant thymoma patient: a case report |
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| รหัสดีโอไอ | |
| Creator | Apisada Sutepvarnon, Krerkchai Sriburom, Peerawan Chochai, Sutima Luangdilok |
| Title | Rare paraneoplastic aplastic anemia in malignant thymoma patient: a case report |
| Publisher | Text and Journal Publication |
| Publication Year | 2558 |
| Journal Title | Vajira Medical Journal |
| Journal Vol. | 58 |
| Journal No. | 4 |
| Page no. | 59-64 |
| Keyword | Aplastic anemia, thymoma, anti-thymocyte globulin, cyclosporine, prognosis |
| ISSN | 0125-1252 |
| Abstract | Aplastic anemia, a rare immune-mediated complication, presented as pancytopenia was described in a patient with malignant thymoma. It may present together with or prior to tumor diagnosis or occur after tumor resection. Immunosuppressive therapy or allogeneic hematopoietic stem cell transplantation is required. In this report, we present the case of a 38-year-old man with an inoperable type B1 thymoma who developed prolonged pancytopenia after two cycles of palliative chemotherapy. Bone marrow biopsy was carried out and severe aplastic anemia was established. The patient was unsuccessfully treated with anti-thymocyte globulin plus cyclosporine. Difficulty in treating remains a problem. Further studies are needed to determine the proper treatment plan. |
